Activation of Indian Hedgehog Promotes Chondrocyte Hypertrophy and Upregulation of MMP-13 in Human Osteoarthritic Cartilage

OBJECTIVE: The objectives of this study were to 1) determine the correlation between osteoarthritis (OA) and Ihh expression, and 2) establish the effects of Ihh on expression of markers of chondrocyte hypertrophy and MMP-13 in human OA cartilage. DESIGN: OA cartilage and synovial fluid samples were...

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Autori principali: Wei, Fangyuan, Zhou, Jingming, Wei, Xiaochun, Zhang, Juntao, Fleming, Braden C., Terek, Richard, Pei, Ming, Chen, Qian, Liu, Tao, Wei, Lei
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374008/
https://ncbi.nlm.nih.gov/pubmed/22469853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2012.03.010
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