The Effects of Indian Hedgehog Deletion on Mesenchyme Cells: Inducing Intermediate Cartilage Scaffold Ossification to Cause Growth Plate and Phalange Joint Absence, Short Limb, and Dwarfish Phenotypes

The endochondral ossification plays a critical role in vertebrate limb development and skeletal homeostasis, where limb mesenchyme cells form an intermediate cartilage scaffold that develops into growth plates and then replaced by bone. Although Indian hedgehog (Ihh) is known to control the hypertro...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Stem Cells Dev
Main Authors: Sun, Jian, Wei, Xiaochun, Li, Shengchun, Sun, Changqi, Wang, Chunfang, Li, Pengcui, Wei, Dennis L., Wei, Lei
פורמט: Artigo
שפה:Inglês
יצא לאור: Mary Ann Liebert, Inc., publishers 2018
נושאים:
Original Research Reports
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205051/
https://ncbi.nlm.nih.gov/pubmed/30032718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2018.0071
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