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The Latency-Associated Transcript Inhibits Apoptosis via Downregulation of Components of the Type I Interferon Pathway during Latent Herpes Simplex Virus 1 Ocular Infection

The herpes simplex virus (HSV-1) latency-associated transcript (LAT) has been shown to inhibit apoptosis via inhibiting activation of proapoptotic caspases. However, the mechanism of LAT control of apoptosis is unclear, because LAT is not known to encode a functional protein, and the LAT transcript...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Tormanen, Kati, Allen, Sariah, Mott, Kevin R., Ghiasi, Homayon
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6498055/
https://ncbi.nlm.nih.gov/pubmed/30814286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00103-19
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