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Coregulatory Interactions among CD8α Dendritic Cells, the Latency-Associated Transcript, and Programmed Death 1 Contribute to Higher Levels of Herpes Simplex Virus 1 Latency

The latency-associated transcript (LAT) of herpes simplex virus 1 (HSV-1), CD8α(+) dendritic cells (DCs), and programmed death 1 (PD-1) have all been implicated in the HSV-1 latency-reactivation cycle. It is not known, however, whether an interaction between LAT and CD8α(+) DCs regulates latency and...

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Autori principali: Mott, Kevin R., Allen, Sariah J., Zandian, Mandana, Ghiasi, Homayon
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054370/
https://ncbi.nlm.nih.gov/pubmed/24672046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00590-14
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