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Role of Interleukin-2 and Herpes Simplex Virus 1 in Central Nervous System Demyelination in Mice

We have reported previously that ocular infection of different strains of mice with recombinant herpes simplex virus 1 (HSV-1) constitutively expressing interleukin-2 (IL-2) provokes central nervous system (CNS) demyelination and optic neuropathy, as determined by changes in visual evoked cortical p...

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Detalhes bibliográficos
Main Authors: Mott, Kevin R., Zandian, Mandana, Allen, Sariah J., Ghiasi, Homayon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807926/
https://ncbi.nlm.nih.gov/pubmed/23986600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02241-13
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