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Immunization with Different Viral Antigens Alters the Pattern of T Cell Exhaustion and Latency in Herpes Simplex Virus Type 1-Infected Mice

We have shown previously that immunization with herpes simplex virus type 1 (HSV-1) glycoprotein K (gK) exacerbated corneal scarring (CS) in ocularly infected mice. In this study, we investigated whether higher levels of CS were correlated with higher levels of latency and T cell exhaustion in gK-im...

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Auteurs principaux: Allen, Sariah J., Mott, Kevin R., Zandian, Mandana, Ghiasi, Homayon
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2010
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976415/
https://ncbi.nlm.nih.gov/pubmed/20861248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01600-10
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