Whole-genome sequencing reveals novel tandem-duplication hotspots and a prognostic mutational signature in gastric cancer

Genome-wide analysis of genomic signatures might reveal novel mechanisms for gastric cancer (GC) tumorigenesis. Here, we analysis structural variations (SVs) and mutational signatures via whole-genome sequencing of 168 GCs. Our data demonstrates diverse models of complex SVs operative in GC, which l...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Nat Commun
Autori principali: Xing, Rui, Zhou, Yong, Yu, Jun, Yu, Yingyan, Nie, Yongzhan, Luo, Wen, Yang, Chao, Xiong, Teng, Wu, William K. K., Li, Zhongwu, Bing, Yang, Lin, Shuye, Zhang, Yaping, Hu, Yingqi, Li, Lin, Han, Lijuan, Yang, Chen, Huang, Shaogang, Huang, Suiping, Zhou, Rui, Li, Jing, Wu, Kaichun, Fan, Daiming, Tang, Guangbo, Dou, Jianhua, Zhu, Zhenggang, Ji, Jiafu, Fang, Xiaodong, Lu, Youyong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497673/
https://ncbi.nlm.nih.gov/pubmed/31048690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09644-6
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi