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Methylation of miR-129-5p CpG island modulates multi-drug resistance in gastric cancer by targeting ABC transporters

Recent studies have reported that hyper-methylation in the promoter region of miRNAs could silence the expression of tumor suppressive miRNAs and might play significant roles in the process of tumor development. However, the potential mechanisms regarding how methylation of miRNA CpG Island could re...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wu, Qiong, Yang, Zhiping, Xia, Lin, Nie, Yongzhan, Wu, Kaichun, Shi, Yongquan, Fan, Daiming
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294356/
https://ncbi.nlm.nih.gov/pubmed/25344911
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