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Characterization of human gastric carcinoma-related methylation of 9 miR CpG islands and repression of their expressions in vitro and in vivo

BACKGROUND: Many miR genes are located within or around CpG islands. It is unclear whether methylation of these CpG islands represses miR transcription regularly. The aims of this study are to characterize gastric carcinoma (GC)-related methylation of miR CpG islands and its relationship with miRNA...

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Detalhes bibliográficos
Main Authors: Du, Yantao, Liu, Zhaojun, Gu, Liankun, Zhou, Jing, Zhu, Bu-dong, Ji, Jiafu, Deng, Dajun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517451/
https://ncbi.nlm.nih.gov/pubmed/22703336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-249
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