Characterization of human gastric carcinoma-related methylation of 9 miR CpG islands and repression of their expressions in vitro and in vivo

BACKGROUND: Many miR genes are located within or around CpG islands. It is unclear whether methylation of these CpG islands represses miR transcription regularly. The aims of this study are to characterize gastric carcinoma (GC)-related methylation of miR CpG islands and its relationship with miRNA...

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Bibliografski detalji
Glavni autori: Du, Yantao, Liu, Zhaojun, Gu, Liankun, Zhou, Jing, Zhu, Bu-dong, Ji, Jiafu, Deng, Dajun
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517451/
https://ncbi.nlm.nih.gov/pubmed/22703336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-249
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