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Characterization of human gastric carcinoma-related methylation of 9 miR CpG islands and repression of their expressions in vitro and in vivo

BACKGROUND: Many miR genes are located within or around CpG islands. It is unclear whether methylation of these CpG islands represses miR transcription regularly. The aims of this study are to characterize gastric carcinoma (GC)-related methylation of miR CpG islands and its relationship with miRNA...

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Auteurs principaux: Du, Yantao, Liu, Zhaojun, Gu, Liankun, Zhou, Jing, Zhu, Bu-dong, Ji, Jiafu, Deng, Dajun
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2012
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517451/
https://ncbi.nlm.nih.gov/pubmed/22703336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-249
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