Nucleosomes Correlate with In Vivo Progression Pattern of De Novo Methylation of p16 CpG Islands in Human Gastric Carcinogenesis

BACKGROUND: The exact relationship between nucleosome positioning and methylation of CpG islands in human pathogenesis is unknown. METHODOLOGY/PRINCIPAL FINDINGS: In the present study, we characterized the nucleosome position within the p16 CpG island and established a seeding methylation-specific P...

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Autori principali: Lu, Zhe-Ming, Zhou, Jing, Wang, Xiuhong, Guan, Zhenpo, Bai, Hua, Liu, Zhao-Jun, Su, Na, Pan, Kaifeng, Ji, Jiafu, Deng, Dajun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338478/
https://ncbi.nlm.nih.gov/pubmed/22558275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035928
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