Methylation of miR-129-5p CpG island modulates multi-drug resistance in gastric cancer by targeting ABC transporters

Recent studies have reported that hyper-methylation in the promoter region of miRNAs could silence the expression of tumor suppressive miRNAs and might play significant roles in the process of tumor development. However, the potential mechanisms regarding how methylation of miRNA CpG Island could re...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Wu, Qiong, Yang, Zhiping, Xia, Lin, Nie, Yongzhan, Wu, Kaichun, Shi, Yongquan, Fan, Daiming
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2014
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294356/
https://ncbi.nlm.nih.gov/pubmed/25344911
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