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CD4 T cell affinity diversity is equally maintained during acute and chronic infection Chronic infection fails to alter T cell affinity diversity

T cell receptor (TCR) affinity for peptide major histocompatibility complex (pMHC) dictates the functional efficiency of T cells and their propensity to differentiate into effectors and form memory. However, in the context of chronic infections it is unclear what the overall profile of TCR affinity...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Andargachew, Rakieb, Martinez, Ryan J., Kolawole, Elizabeth M., Evavold, Brian D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497530/
https://ncbi.nlm.nih.gov/pubmed/29777029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800295
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