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Low Affinity Memory CD8(+) T Cells Mediate Robust Heterologous Immunity
Heterologous immunity is recognized as a significant barrier to transplant tolerance. While pathogen elicited memory T cells can have high or low affinity for cross-reactive allogeneic peptide:MHC, the role T cell receptor (TCR) affinity during heterologous immunity has not been explored. We establi...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4779681/ https://ncbi.nlm.nih.gov/pubmed/26864034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500639 |
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