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Enhanced Requirement for TNFR2 in Graft Rejection Mediated by Low Affinity Memory CD8(+) T Cells During Heterologous Immunity
The affinity of a T cell receptor (TCR) binding to peptide:MHC profoundly impacts the phenotype and function of effector and memory cell differentiation. Little is known about the effect of low affinity priming on memory cell generation and function, which is particularly important in heterologous i...
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| Udgivet i: | J Immunol |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4992585/ https://ncbi.nlm.nih.gov/pubmed/27481849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502680 |
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