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Enhanced Requirement for TNFR2 in Graft Rejection Mediated by Low Affinity Memory CD8(+) T Cells During Heterologous Immunity
The affinity of a T cell receptor (TCR) binding to peptide:MHC profoundly impacts the phenotype and function of effector and memory cell differentiation. Little is known about the effect of low affinity priming on memory cell generation and function, which is particularly important in heterologous i...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4992585/ https://ncbi.nlm.nih.gov/pubmed/27481849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502680 |
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