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Combined LFA-1 and costimulatory blockade prevents transplant rejection mediated by heterologous immune memory alloresponses
BACKGROUND: Recent evidence suggests that alloreactive memory T cells are generated by the process of heterologous immunity, whereby memory T cells arising in response to pathogen infection cross-react with donor antigens. Due to their diminished requirements for costimulation during recall, these p...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3703766/ https://ncbi.nlm.nih.gov/pubmed/22475765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e31824e75d7 |
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