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Anti-LFA-1 Therapy in a Nonhuman Primate Renal Transplant Model of Costimulation Blockade Resistant Rejection
Costimulation blockade with the fusion protein belatacept provides a desirable side-effect profile and improvement in renal function compared to calcineurin inhibition in renal transplantation. This comes at the cost of increased rates of early acute rejection. Blockade of the integrin molecule LFA-...
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| Publicado no: | Am J Transplant |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5066576/ https://ncbi.nlm.nih.gov/pubmed/26602755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.13628 |
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