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Integrin antagonists prevent costimulatory blockade-resistant transplant rejection by CD8(+) memory T cells
The success of belatacept in late-stage clinical trials inaugurates the arrival of a new class of immunosuppressants based on costimulatory blockade, an immunosuppression strategy that disrupts essential signals required for alloreactive T cell activation. Despite having improved renal function, kid...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3467016/ https://ncbi.nlm.nih.gov/pubmed/21942986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2011.03762.x |
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