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Pathogen stimulation history impacts donor-specific CD8(+) T cell susceptibility to costimulation/integrin blockade-based therapy

Recent studies have shown that the quantity of donor-reactive memory T cells is an important factor in determining the relative heterologous immunity barrier posed during transplantation. Here, we hypothesized that the quality of T cell memory also potently influences the response to costimulation b...

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Detalhes bibliográficos
Publicado no:Am J Transplant
Main Authors: Badell, IR, Kitchens, WH, Wagener, ME, Lukacher, AE, Larsen, CP, Ford, ML
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5416935/
https://ncbi.nlm.nih.gov/pubmed/26228897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.13399
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