Anti-CD40-based Costimulation Blockade Enhances Neonatal Porcine Islet Survival in Nonhuman Primates

The widespread clinical implementation of alloislet transplantation as therapy for type 1 diabetes has been hindered by the lack of suitable islet donors. Pig-to-human islet xenotransplantation is one strategy with potential to alleviate this shortage. Long-term survival of porcine islets has been a...

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Dettagli Bibliografici
Pubblicato in:Am J Transplant
Autori principali: Thompson, P, Cardona, K, Russell, M, Badell, IR, Shaffer, V, Korbutt, G, Cano, J, Song, M, Jiang, W, Strobert, E, Rajotte, R, Pearson, T, Kirk, AD, Larsen, CP
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845096/
https://ncbi.nlm.nih.gov/pubmed/21521467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2011.03509.x
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