CTLA4Ig Prevents Alloantibody Formation Following Nonhuman Primate Islet Transplantation Using the CD40-specific Antibody 3A8

Islet transplantation to treat type 1 diabetes has been limited in part by toxicities of current immunosuppression and recipient humoral sensitization. Blockade of the CD28/CD80/86 and CD40/CD154 pathways has shown promise to remedy both these limitations, but translation has been hampered by diffic...

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Autori principali: Badell, IR, Russell, MC, Cardona, K, Shaffer, VO, Turner, AP, Avila, JG, Cano, JA, Leopardi, FV, Song, M, Strobert, EA, Ford, ML, Pearson, TC, Kirk, AD, Larsen, CP
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387300/
https://ncbi.nlm.nih.gov/pubmed/22458552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2012.04029.x
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