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Costimulation Blockade in Autoimmunity and Transplantation: The CD28 Pathway

T cell activation is a complex process that requires multiple cell signaling pathways, including a primary recognition signal and additional costimulatory signals. TCR signaling in the absence of costimulatory signals can lead to an abortive attempt at activation and subsequent anergy. One of the be...

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Библиографические подробности
Опубликовано в: :J Immunol
Главные авторы: Adams, Andrew B., Ford, Mandy L., Larsen, Christian P.
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5370073/
https://ncbi.nlm.nih.gov/pubmed/27591335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601135
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