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Costimulation Blockade in Autoimmunity and Transplantation: The CD28 Pathway
T cell activation is a complex process that requires multiple cell signaling pathways, including a primary recognition signal and additional costimulatory signals. TCR signaling in the absence of costimulatory signals can lead to an abortive attempt at activation and subsequent anergy. One of the be...
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Publicado no: | J Immunol |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5370073/ https://ncbi.nlm.nih.gov/pubmed/27591335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601135 |
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