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CD28 Blockade Induces Division-Dependent Down-Regulation of Interleukin-2 Receptor Alpha

BACKGROUND: Blockade of T cell costimulatory molecules represents a promising new method of attenuating donor-reactive T cell responses to promote graft survival following transplantation. However, recent studies in murine models have shown the presence of an initial high frequency of naïve donor-re...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ford, Mandy L., Stempora, Linda L., Larsen, Christian P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056335/
https://ncbi.nlm.nih.gov/pubmed/21073953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trim.2010.11.002
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