लोड हो रहा है...
Selective CD28 blockade attenuates CTLA-4–dependent CD8(+) memory T cell effector function and prolongs graft survival
Memory T cells pose a significant problem to successful therapeutic control of unwanted immune responses during autoimmunity and transplantation, as they are differentially controlled by cosignaling receptors such as CD28 and CTLA-4. Treatment with abatacept and belatacept impede CD28 signaling by b...
में बचाया:
| में प्रकाशित: | JCI Insight |
|---|---|
| मुख्य लेखकों: | , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Society for Clinical Investigation
2018
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5821191/ https://ncbi.nlm.nih.gov/pubmed/29321374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.96378 |
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