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High Frequency Alloreactive T Cells Augment Effector Function of Low Frequency CD8(+) T Cell Responses Under CD28/CD154 Blockade
BACKGROUND: Blockade of costimulatory molecules is a potent method of inducing long-term graft survival. We have previously addressed the issue of donor-reactive T cell precursor frequency on relative costimulation dependence, and found that the presence of a high precursor frequency of donor-reacti...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2935314/ https://ncbi.nlm.nih.gov/pubmed/20407401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e3181df53dc |
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