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CD154 Blockade Alters Innate Immune Cell Recruitment and Programs Alloreactive CD8(+) T Cells into KLRG-1(high) Short-Lived Effector T Cells

CD154/CD40 blockade combined with donor specific transfusion remains one of the most effective therapies in prolonging allograft survival. Despite this, the mechanisms by which these pathways synergize to prevent rejection are not completely understood. Utilizing a BALB/c (H2-K(d)) to B6 (H2-K(b)) f...

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Autori principali: Ferrer, Ivana R., Wagener, Maylene E., Song, Mingqing, Ford, Mandy L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390379/
https://ncbi.nlm.nih.gov/pubmed/22792369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040559
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