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CD154 Blockade Alters Innate Immune Cell Recruitment and Programs Alloreactive CD8(+) T Cells into KLRG-1(high) Short-Lived Effector T Cells

CD154/CD40 blockade combined with donor specific transfusion remains one of the most effective therapies in prolonging allograft survival. Despite this, the mechanisms by which these pathways synergize to prevent rejection are not completely understood. Utilizing a BALB/c (H2-K(d)) to B6 (H2-K(b)) f...

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Detalhes bibliográficos
Main Authors: Ferrer, Ivana R., Wagener, Maylene E., Song, Mingqing, Ford, Mandy L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390379/
https://ncbi.nlm.nih.gov/pubmed/22792369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040559
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