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Antigen-specific induced Foxp3(+) regulatory T cells are generated following CD40/CD154 blockade

Blockade of the CD40/CD154 pathway potently attenuates T-cell responses in models of autoimmunity, inflammation, and transplantation. Indeed, CD40 pathway blockade remains one of the most powerful methods of prolonging graft survival in models of transplantation. But despite this effectiveness, the...

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Autori principali: Ferrer, Ivana R., Wagener, Maylene E., Song, Minqing, Kirk, Allan D., Larsen, Christian P., Ford, Mandy L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251074/
https://ncbi.nlm.nih.gov/pubmed/22143783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1105500108
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