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Antigen-specific induced Foxp3(+) regulatory T cells are generated following CD40/CD154 blockade

Blockade of the CD40/CD154 pathway potently attenuates T-cell responses in models of autoimmunity, inflammation, and transplantation. Indeed, CD40 pathway blockade remains one of the most powerful methods of prolonging graft survival in models of transplantation. But despite this effectiveness, the...

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Autores principales: Ferrer, Ivana R., Wagener, Maylene E., Song, Minqing, Kirk, Allan D., Larsen, Christian P., Ford, Mandy L.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251074/
https://ncbi.nlm.nih.gov/pubmed/22143783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1105500108
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