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A Critical Precursor Frequency of Donor-Reactive CD4(+) T Cell Help is Required for CD8(+) T Cell-Mediated CD28/CD154-Independent Rejection

Antigen-specific precursor frequency is increasingly being appreciated as an important factor in determining the kinetics, magnitude, and degree of differentiation of T cell responses, and recently was found to play a critical role in determining the relative requirement of CD8(+) T cells for CD28-...

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Detalhes bibliográficos
Main Authors: Ford, Mandy L., Wagener, Maylene E., Hanna, Samantha S., Pearson, Thomas C., Kirk, Allan D., Larsen, Christian P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570960/
https://ncbi.nlm.nih.gov/pubmed/18490719
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