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Low-affinity CD4+ T cells are major responders in the primary immune response
A robust primary immune response has been correlated with the precursor number of antigen-specific T cells, as identified using peptide MHCII tetramers. However, these tetramers identify only the highest-affinity T cells. Here we show the entire CD4+ T-cell repertoire, inclusive of low-affinity T ce...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5234832/ https://ncbi.nlm.nih.gov/pubmed/27976744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13848 |
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