Viral Escape Mutant Epitope Maintains TCR Affinity for Antigen yet Curtails CD8 T Cell Responses

T cells have the remarkable ability to recognize antigen with great specificity and in turn mount an appropriate and robust immune response. Critical to this process is the initial T cell antigen recognition and subsequent signal transduction events. This antigen recognition can be modulated at the...

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Bibliographic Details
Published in:PLoS One
Main Authors: Shorter, Shayla K., Schnell, Frederick J., McMaster, Sean R., Pinelli, David F., Andargachew, Rakieb, Evavold, Brian D.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767940/
https://ncbi.nlm.nih.gov/pubmed/26915099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149582
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