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Lower Affinity T Cells are Critical Components and Active Participants of the Immune Response
Kinetic and biophysical parameters of T cell receptor (TCR) and peptide:MHC (pMHC) interaction define intrinsic factors required for T cell activation and differentiation. Although receptor ligand kinetics are somewhat cumbersome to assess experimentally, TCR:pMHC affinity has been shown to predict...
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| Опубликовано в: : | Front Immunol |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Frontiers Media S.A.
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4564719/ https://ncbi.nlm.nih.gov/pubmed/26441973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00468 |
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