CD45RB Status of CD8(+) T Cell Memory Defines T Cell Receptor Affinity and Persistence

The identity of CD45 isoforms on the T cell surface changes following the activation of naive T cells and impacts intracellular signaling. In this study, we find that the anti-viral memory CD8(+) T pool is unexpectedly comprised of both CD45RB(hi) and CD45RB(lo) populations. Relative to CD45RB(lo) m...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Cell Rep
Päätekijät: Krummey, Scott M., Morris, Anna B., Jacobs, Jesica R., McGuire, Donald J., Ando, Satomi, Tong, Katherine P., Zhang, Weiwen, Robertson, Jennifer, Guasch, Sara A, Araki, Koichi, Larsen, Christian P., Evavold, Brian D., Kissick, Haydn T., Ford, Mandy L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2020
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7155808/
https://ncbi.nlm.nih.gov/pubmed/32023448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.01.016
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