CD45RB Status of CD8(+) T Cell Memory Defines T Cell Receptor Affinity and Persistence

The identity of CD45 isoforms on the T cell surface changes following the activation of naive T cells and impacts intracellular signaling. In this study, we find that the anti-viral memory CD8(+) T pool is unexpectedly comprised of both CD45RB(hi) and CD45RB(lo) populations. Relative to CD45RB(lo) m...

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Publicado en:Cell Rep
Main Authors: Krummey, Scott M., Morris, Anna B., Jacobs, Jesica R., McGuire, Donald J., Ando, Satomi, Tong, Katherine P., Zhang, Weiwen, Robertson, Jennifer, Guasch, Sara A, Araki, Koichi, Larsen, Christian P., Evavold, Brian D., Kissick, Haydn T., Ford, Mandy L.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7155808/
https://ncbi.nlm.nih.gov/pubmed/32023448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.01.016
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