The γ-secretase-cleaved C-terminal fragment of amyloid precursor protein mediates signaling to the nucleus

Eitemau Tebyg

• Molecular mechanism of the intramembrane cleavage of the β-carboxyl terminal fragment of amyloid precursor protein by γ-secretase
  gan: Morishima-Kawashima, Maho
  Cyhoeddwyd: (2014)
• A γ-Secretase-independent Mechanism of Signal Transduction by the Amyloid Precursor Protein
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  Cyhoeddwyd: (2005)
• Processing of Notch and amyloid precursor protein by γ-secretase is spatially distinct
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  Cyhoeddwyd: (2004)
• The γ-secretase-generated intracellular domain of β-amyloid precursor protein binds Numb and inhibits Notch signaling
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  Cyhoeddwyd: (2002)
• Delta-secretase cleaves amyloid precursor protein and regulates the pathogenesis in Alzheimer's disease
  gan: Zhang, Zhentao, et al.
  Cyhoeddwyd: (2015)