טוען...
Delta-secretase cleaves amyloid precursor protein and regulates the pathogenesis in Alzheimer's disease
The age-dependent deposition of amyloid-β peptides, derived from amyloid precursor protein (APP), is a neuropathological hallmark of Alzheimer's disease (AD). Despite age being the greatest risk factor for AD, the molecular mechanisms linking ageing to APP processing are unknown. Here we show t...
שמור ב:
| הוצא לאור ב: | Nat Commun |
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| Main Authors: | , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Pub. Group
2015
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4659940/ https://ncbi.nlm.nih.gov/pubmed/26549211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9762 |
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