In Vitro Activity of Combinations of Zinc Chelators with Amphotericin B and Posaconazole against Six Mucorales Species

Mucormycosis is an emerging disease with high mortality rates. Few antifungal drugs are active against Mucorales. Considering the low efficacy of monotherapy, combination-therapy strategies have been described. It is known that fungi are susceptible to zinc deprivation, so we tested the in vitro eff...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Leonardelli, Florencia, Macedo, Daiana, Dudiuk, Catiana, Theill, Laura, Cabeza, Matias S., Gamarra, Soledad, Garcia-Effron, Guillermo
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2019
Témata:
Susceptibility
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496101/
https://ncbi.nlm.nih.gov/pubmed/30885898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00266-19
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