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In Vitro and In Vivo Evaluation of Voriconazole-Containing Antifungal Combinations against Mucorales Using a Galleria mellonella Model of Mucormycosis

Mucorales are resistant to most antifungals. Mucormycosis associated mortality is unacceptable and new treatment approaches are needed. The objectives of this work were (i) to evaluate the nature and intensity of the in vitro effect of three drugs combinations which included voriconazole (plus ampho...

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Detalhes bibliográficos
Publicado no:J Fungi (Basel)
Main Authors: Macedo, Daiana, Leonardelli, Florencia, Dudiuk, Catiana, Vitale, Roxana G., Del Valle, Eleodoro, Giusiano, Gustavo, Gamarra, Soledad, Garcia-Effron, Guillermo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6462937/
https://ncbi.nlm.nih.gov/pubmed/30626083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jof5010005
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