Quick Detection of FKS1 Mutations Responsible for Clinical Echinocandin Resistance in Candida albicans

A rapid molecular-based assay for the detection of the Candida albicans FKS1 gene mutations responsible for resistance to echinocandin drugs was designed and evaluated. The assay consisted of a multiplexed PCR set of 5 tubes able to detect the most commonly described resistance mechanism, including...

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Detalhes bibliográficos
Publicado no:J Clin Microbiol
Main Authors: Dudiuk, Catiana, Gamarra, Soledad, Jimenez-Ortigosa, Cristina, Leonardelli, Florencia, Macedo, Daiana, Perlin, David S., Garcia-Effron, Guillermo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Mycology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4473184/
https://ncbi.nlm.nih.gov/pubmed/25878347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00398-15
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