Fitness and Virulence Costs of Candida albicans FKS1 Hot Spot Mutations Associated With Echinocandin Resistance

(See the editorial commentary by Clancy and Hong Nguyen, on pages 499–501.) The identification of FKS1 mutations in Candida albicans associated with echinocandin resistance has raised concerns over the spread of drug-resistant strains. We studied the impact of fks1 mutations on C. albicans virulence...

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Bibliographic Details
Main Authors: Ben-Ami, Ronen, Garcia-Effron, Guillermo, Lewis, Russell E., Gamarra, Soledad, Leventakos, Konstantinos, Perlin, David S., Kontoyiannis, Dimitrios P.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2011
Subjects:
Major Articles and Brief Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144175/
https://ncbi.nlm.nih.gov/pubmed/21791665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir351
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