Fitness and Virulence Costs of Candida albicans FKS1 Hot Spot Mutations Associated With Echinocandin Resistance

(See the editorial commentary by Clancy and Hong Nguyen, on pages 499–501.) The identification of FKS1 mutations in Candida albicans associated with echinocandin resistance has raised concerns over the spread of drug-resistant strains. We studied the impact of fks1 mutations on C. albicans virulence...

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Autori principali: Ben-Ami, Ronen, Garcia-Effron, Guillermo, Lewis, Russell E., Gamarra, Soledad, Leventakos, Konstantinos, Perlin, David S., Kontoyiannis, Dimitrios P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2011
Soggetti:
Major Articles and Brief Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144175/
https://ncbi.nlm.nih.gov/pubmed/21791665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir351
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