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FKS2 and FKS3 Genes of Opportunistic Human Pathogen Candida albicans Influence Echinocandin Susceptibility

Candida albicans, a prevailing opportunistic fungal pathogen of humans, has a diploid genome containing three homologous FKS genes that are evolutionarily conserved. One of these, the essential gene FKS1, encodes the catalytic subunit of glucan synthase, which is the target of echinocandin drugs and...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Suwunnakorn, Sumanun, Wakabayashi, Hironao, Kordalewska, Milena, Perlin, David S., Rustchenko, Elena
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913916/
https://ncbi.nlm.nih.gov/pubmed/29358288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02299-17
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