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Chromosome 5 of Human Pathogen Candida albicans Carries Multiple Genes for Negative Control of Caspofungin and Anidulafungin Susceptibility

Candida albicans is an important fungal pathogen with a diploid genome that can adapt to caspofungin, a major drug from the echinocandin class, by a reversible loss of one copy of chromosome 5 (Ch5). Here, we explore a hypothesis that more than one gene for negative regulation of echinocandin tolera...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Suwunnakorn, Sumanun, Wakabayashi, Hironao, Rustchenko, Elena
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5119030/
https://ncbi.nlm.nih.gov/pubmed/27736768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01888-16
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