Anidulafungin versus Caspofungin in a Mouse Model of Candidiasis Caused by Anidulafungin-Susceptible Candida parapsilosis Isolates with Different Degrees of Caspofungin Susceptibility

Candida parapsilosis isolates occasionally display resistance in vitro to echinocandins and cause breakthrough infections to echinocandins. The degree of the in vivo cross-resistance among echinocandins and the fitness loss associated with caspofungin (CAS) resistance of C. parapsilosis are not well...

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Bibliographic Details
Main Authors: Dimopoulou, Dimitra, Hamilos, Georgios, Tzardi, Maria, Lewis, Russell E., Samonis, George, Kontoyiannis, Dimitrios P.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
Subjects:
Mechanisms of Action: Physiological Effects
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910758/
https://ncbi.nlm.nih.gov/pubmed/24145540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01025-13
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