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FKS2 and FKS3 Genes of Opportunistic Human Pathogen Candida albicans Influence Echinocandin Susceptibility

Candida albicans, a prevailing opportunistic fungal pathogen of humans, has a diploid genome containing three homologous FKS genes that are evolutionarily conserved. One of these, the essential gene FKS1, encodes the catalytic subunit of glucan synthase, which is the target of echinocandin drugs and...

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Suwunnakorn, Sumanun, Wakabayashi, Hironao, Kordalewska, Milena, Perlin, David S., Rustchenko, Elena
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913916/
https://ncbi.nlm.nih.gov/pubmed/29358288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02299-17
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