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Pyrosequencing To Detect Mutations in FKS1 That Confer Reduced Echinocandin Susceptibility in Candida albicans

Pyrosequencing was compared to Sanger dideoxy sequencing to detect mutations in FKS1 responsible for reduced echinocandin susceptibility in Candida albicans. These methods were in complete agreement for 10 of 12 clinical isolates with elevated echinocandin MICs, supporting the potential feasibility...

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Detalhes bibliográficos
Main Authors: Wiederhold, Nathan P., Grabinski, Jodi L., Garcia-Effron, Guillermo, Perlin, David S., Lee, Samuel A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573102/
https://ncbi.nlm.nih.gov/pubmed/18794385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00959-08
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