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Pyrosequencing To Detect Mutations in FKS1 That Confer Reduced Echinocandin Susceptibility in Candida albicans

Pyrosequencing was compared to Sanger dideoxy sequencing to detect mutations in FKS1 responsible for reduced echinocandin susceptibility in Candida albicans. These methods were in complete agreement for 10 of 12 clinical isolates with elevated echinocandin MICs, supporting the potential feasibility...

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Bibliografiske detaljer
Main Authors: Wiederhold, Nathan P., Grabinski, Jodi L., Garcia-Effron, Guillermo, Perlin, David S., Lee, Samuel A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573102/
https://ncbi.nlm.nih.gov/pubmed/18794385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00959-08
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