FKS2 and FKS3 Genes of Opportunistic Human Pathogen Candida albicans Influence Echinocandin Susceptibility

Candida albicans, a prevailing opportunistic fungal pathogen of humans, has a diploid genome containing three homologous FKS genes that are evolutionarily conserved. One of these, the essential gene FKS1, encodes the catalytic subunit of glucan synthase, which is the target of echinocandin drugs and...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Suwunnakorn, Sumanun, Wakabayashi, Hironao, Kordalewska, Milena, Perlin, David S., Rustchenko, Elena
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2018
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913916/
https://ncbi.nlm.nih.gov/pubmed/29358288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02299-17
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