Molecular Confirmation of the Linkage between the Rhizopus oryzae CYP51A Gene Coding Region and Its Intrinsic Voriconazole and Fluconazole Resistance

Rhizopus oryzae is the most prevalent causative agent of mucormycosis, an increasingly reported opportunistic fungal infection. These Mucorales are intrinsically resistant to Candida- and Aspergillus-active antifungal azole drugs, such as fluconazole (FLC) and voriconazole, respectively. Despite its...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Macedo, Daiana, Leonardelli, Florencia, Dudiuk, Catiana, Theill, Laura, Cabeza, Matías S., Gamarra, Soledad, Garcia-Effron, Guillermo
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2018
Témata:
Mechanisms of Resistance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105841/
https://ncbi.nlm.nih.gov/pubmed/29891608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00224-18
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