Hepatotoxicity Induced by Isoniazid-Lipopolysaccharide through Endoplasmic Reticulum Stress, Autophagy, and Apoptosis Pathways in Zebrafish

Isoniazid (INH) is a first-line antituberculosis drug. The incidence of adverse reactions accompanied by inflammation in the liver during drug administration to tuberculosis patients is high and severely affects clinical treatment. To better understand the mechanism of hepatotoxicity induced by INH...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Zhang, Yun, Cen, Juan, Jia, Zhili, Hsiao, Chung-Der, Xia, Qing, Wang, Xue, Chen, Xiqiang, Wang, Rongchun, Jiang, Zhenzhou, Zhang, Luyong, Liu, Kechun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496066/
https://ncbi.nlm.nih.gov/pubmed/30858204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01639-18
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