Dexamethasone Pretreatment Alleviates Isoniazid/Lipopolysaccharide Hepatotoxicity: Inhibition of Inflammatory and Oxidative Stress

Isoniazid (INH) remains a cornerstone key constitute of the current tuberculosis management strategy, but its hepatotoxic potentiality remains a significant clinical problem. Our previous findings succeed to establish a rat model of INH hepatotoxicity employing the inflammatory stress theory in whic...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Hassan, Hozeifa M., Guo, Hongli, Yousef, Bashir A., Ping-Ping, Ding, Zhang, Luyong, Jiang, Zhenzhou
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5350150/
https://ncbi.nlm.nih.gov/pubmed/28360859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00133
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